Electromechanical cell lysis using a portable audio device: enabling challenging sample preparation at the point-of-care.

Buser, J R; Wollen, A; Heiniger, E K; Byrnes, S A; Kauffman, P C; Ladd, P D; Yager, P · Lab Chip · 2015

basic_science · Level V

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Abstract

Audio sources are ubiquitously available on portable electronic devices, including cell phones. Here we demonstrate lysis of Mycobacterium marinum and Staphylococcus epidermidis bacteria utilizing a portable audio device coupled with a simple and inexpensive electromagnetic coil. The resulting alternating magnetic field rotates a magnet in a tube with the sample and glass beads, lysing the cells and enabling sample preparation for these bacteria anywhere there is a cell phone, mp3 player, laptop, or other device with a headphone jack.

Medical subject headings