RiboTools: a Galaxy toolbox for qualitative ribosome profiling analysis.
basic_science · Level V
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- Record sourced from PubMed, PMID 25812744.
- Also identified by DOI 10.1093/bioinformatics/btv174.
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Abstract
Ribosome profiling provides genome-wide information about translational regulation. However, there is currently no standard tool for the qualitative analysis of Ribo-seq data. We present here RiboTools, a Galaxy toolbox for the analysis of ribosome profiling (Ribo-seq) data. It can be used to detect translational ambiguities, stop codon readthrough events and codon occupancy. It provides a large number of plots for the visualisation of these events.
Medical subject headings
- Computational Biology
- Gene Expression Profiling
- Genome, Fungal
- Ribosomes
- Saccharomyces cerevisiae
- Software