Experimental modulation and computational model of nano-hydrophobicity.

Li, Shuhuan; Zhai, Shumei; Liu, Yin; Zhou, Hongyu; Wu, Jinmei; Jiao, Qing; Zhang, Bin; Zhu, Hao et al. · Biomaterials · 2015

basic_science · Level V

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Abstract

We demonstrate that nano-hydrophobicity, which governs the biological aggressiveness of nanoparticles, is determined by the outermost regions of surface ligands. We have also successfully modulated nano-hydrophobicity using systematic surface ligand modifications and built the first computational model of nano-hydrophobicity.

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