Meter-long multiblock copolymer microfibers via interfacial bioorthogonal polymerization.

Liu, Shuang; Zhang, Han; Remy, Roddel A; Deng, Fei; Mackay, Michael E; Fox, Joseph M; Jia, Xinqiao · Adv Mater · 2015

basic_science · Level V

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Abstract

High-molecular-weight multiblock copolymers are synthesized as robust polymer fibers via interfacial bioorthogonal polymerization employing the rapid cycloaddition of s-tetrazines with strained trans-cyclooctenes. When cell-adhesive peptide is incorporated in the tetrazine monomer, the resulting protein-mimetic polymer fibers provide guidance cues for cell attachment and elongation.

Medical subject headings