Coronary artery stenosis: a new risk factor for chronic kidney injury?
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 25826540.
- Also identified by DOI 10.1038/ki.2014.431.
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Abstract
Coronary artery stenosis induces renal inflammation and kidney injury in pigs even in the absence of myocardial infarction or clinically significant heart failure. This effect is aggravated by experimentally induced renovascular hypertension. Interestingly, oxidative stress originating from the ischemic myocardium was identified as a possible mediator of this new pathophysiological link between heart and kidney. Renin-angiotensin or sympathetic nervous system activation did not appear to play a role in the observed cardio-renal link.
Medical subject headings
- Acute Kidney Injury
- Coronary Stenosis
- Hypertension, Renovascular
- Kidney