Take my breath away: necrosis in kidney transplants kills the lungs!
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25826542.
- Also identified by DOI 10.1038/ki.2015.13.
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Abstract
Necrosis is not only a regulated process, it is an interconnected molecular network allowing different genetically encoded forms that are more or less immunogenic. Zhao et al. elegantly illustrate this concept, underscore the need for combination therapy to successfully interfere with regulated necrosis, and identify the role of regulated necrosis in the pathophysiology of remote lung injury.
Medical subject headings
- Acute Lung Injury
- DNA Fragmentation
- Kidney Transplantation
- Lung
- Reperfusion Injury