A 3-step therapeutic strategy for severe alveolar proteinosis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 25841841.
- Also identified by DOI 10.1016/j.athoracsur.2014.12.080.
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Abstract
Pulmonary alveolar proteinosis (PAP) is characterized by accumulation of lipoproteinaceous material in the terminal airways. Whole lung lavage (WLL) remains the gold standard treatment but may be particularly challenging in cases of severe hypoxemia. We present a 3-step strategy that was used in a patient with PAP-associated refractory hypoxemia and that combined venovenous extracorporeal membrane oxygenation (vvECMO), double-lumen orotracheal intubation, and bilateral multisegmental sequential lavage (MSL). The procedure was well tolerated and permitted weaning from the ventilator.
Medical subject headings
- Bronchoalveolar Lavage
- Extracorporeal Membrane Oxygenation
- Intubation, Intratracheal
- Pulmonary Alveolar Proteinosis