Next-Generation Sequencing: Targeting Targeted Therapies.

McCutcheon, Justine N; Giaccone, Giuseppe · Clin Cancer Res · 2015

review · Level V

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Abstract

Next-generation sequencing (NGS) has given new perspective in oncology. With the ongoing development of targeted therapies, NGS is evolving molecular diagnostics by providing comprehensive interrogation of clinically actionable genomic aberrations in tumors. Having this assay as the primary testing method produces clinically beneficial results. See related article by Drilon et al., p. 3631.

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