Intracellular bacteria find the right motion.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25860603.
- Also identified by DOI 10.1016/j.cell.2015.03.035.
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Abstract
Benanti et al. report that Burkholderia pseudomallei and Burkholderia mallei bacteria express proteins that mimic Ena/Vasp family proteins to polymerize actin, thereby inducing actin-based motility. Thus, bacteria can use the various cellular actin polymerization mechanisms for intra- and inter-cellular dissemination.
Medical subject headings
- Actins
- Burkholderia
- Burkholderia Infections
- Cell Adhesion Molecules
- Microfilament Proteins
- Phosphoproteins