SnapShot: Origins of DNA replication.

Creager, Rachel L; Li, Yulong; MacAlpine, David M · Cell · 2015

basic_science · Level V

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Abstract

The fundamental unit of DNA replication, the replicon, is governed by a cis-acting replicator sequence and a trans-activating initiator factor. Despite the increased size and complexity of eukaryotic genomes, eukaryotic DNA replication continues to be guided by the fundamental principles and concepts established in the replicon model.

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