Matrix-assisted laser desorption/ionization time of flight mass-spectrometry (MALDI-TOF MS) based typing of extended-spectrum β-lactamase producing E. coli--a novel tool for real-time outbreak investigation.
Where this comes from
- Record sourced from PubMed, PMID 25860943.
- Also identified by DOI 10.1371/journal.pone.0120624 and PMC identifier 4393243.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Epidemiologically linked clusters are confirmed by typing strains with molecular typing such as pulsed-field gel electrophoresis (PFGE). We compared six extended-spectrum β-lactamase producing E. coli of a PFGE-related cluster with Matrix-assisted laser desorption/ionization-time of flight mass-spectrometry based typing that confirmed relatedness faster and more cost-effective, but as reliable as PFGE.
Medical subject headings
- Escherichia coli
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- beta-Lactamases