The mortality of neonatal herpes simplex virus infection.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 25868428.
- Also identified by DOI 10.1016/j.jpeds.2015.03.004.
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Abstract
This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤ 48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.
Medical subject headings
- Herpes Simplex
- Pregnancy Complications, Infectious