Co₉ Se₈ nanoplates as a new theranostic platform for photoacoustic/magnetic resonance dual-modal-imaging-guided chemo-photothermal combination therapy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25885638.
- Also identified by DOI 10.1002/adma.201405634 and PMC identifier 5242345.
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Abstract
A new theranostic platform is developed based on biocompatible poly(acrylic acid) (PAA)-Co9 Se8 nanoplates. These PAA-Co9 Se8 nanoplates are successfully utilized for photoacoustic imaging (PAI)/magnetic resonance imaging (MRI) dual-modal imaging. Moreover, the PAA-Co9 Se8 -DOX shows pH-responsive chemotherapy and enables the combination of photothermal therapy and chemotherapy to receive superior antitumor efficacy. This work promises further exploration of 2D nanoplatforms for theranostic applications.
Medical subject headings
- Cobalt
- Magnetic Resonance Imaging
- Nanostructures
- Photoacoustic Techniques
- Selenium Compounds
- Theranostic Nanomedicine