Risk Factors for Recurrence of Periprosthetic Knee Infection.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 25891435.
- Also identified by DOI 10.1016/j.arth.2015.04.005.
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Abstract
We retrospectively reviewed 110 patients who underwent two-stage revision surgery in order to identify potential risk factors for recurrence of periprosthetic infection. We found that patients with inflammatory arthritis (P=0.0125), perioperative hematoma formation (P=0.0422), wound dehiscence (P=0.042), and those who are chronic Staphylococcus carriers (P=0.0177) were associated with an increased incidence of re-infection. The duration of intravenous antibiotic therapy less than 6 weeks was associated with a reduced risk of reinfection to greater than 6 weeks (P=0.03). Multivariate analysis indicated that wound dehiscence (odds ratio [OR], 5.119; 95% confidence interval [CI], 1.367-19.17), and Staphylococcus carriers (OR, 11.419; 95% CI, 1.376-94.727) are significant predictors of recurrence (P=0.0153 and 0.0241, respectively).
Medical subject headings
- Arthroplasty, Replacement, Knee
- Knee Prosthesis
- Prosthesis-Related Infections
- Staphylococcal Infections
Anatomy
- knee