Genetics and hepatitis C: it's good to be 'CC'.

Parungao, Jose Mari; Hanouneh, Ibrahim A; John, Binu; Alkhouri, Naim; Zein, Nizar N · Cleve Clin J Med · 2015

review · Level V

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Abstract

The interleukin-28B (IL28B) gene contains a single-nucleotide polymorphism at location rs12979860 that affects both the natural history of hepatitis C virus infection and the patient's response to treatment, particularly interferon-based regimens with or without protease inhibitors.

Medical subject headings