Past and future impact of next-generation sequencing in head and neck cancer.
review · Level V
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- Record sourced from PubMed, PMID 25900457.
- Also identified by DOI 10.1002/hed.24085.
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Abstract
Progress in sequencing technology is intrinsically linked to progress in understanding cancer genomics. The purpose of this review was to discuss the development from Sanger sequencing to next-generation sequencing (NGS) technology. We highlight the technical considerations for understanding reports using NGS. We discuss the findings of studies in head and neck cancer using NGS as well as The Cancer Genome Atlas. Finally we discuss future routes for research utilizing this methodology and the potential impact of this. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2395-E2402, 2016.
Medical subject headings
- Head and Neck Neoplasms
- High-Throughput Nucleotide Sequencing