Immune Mechanisms Are Major Players in Cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25904750.
- Also identified by DOI 10.1158/1078-0432.CCR-15-0531 and PMC identifier 4537829.
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Abstract
Vaccination with sipuleucel-T produced IgG antibodies to secondary prostatic carcinoma antigens and prolonged survival in some patients, and assaying for antibodies may provide prognostic information and identify new vaccine targets. Additional approaches to improve T-cell responses are needed to improve the clinical efficacy. See related article by GuhaThakurta et al., p. 3619.
Medical subject headings
- Antigens, Neoplasm
- Immunity, Humoral
- Immunoglobulin G
- Prostatic Neoplasms, Castration-Resistant