Science to practice: myeloperoxidase immunoradiology improves detection of acute and chronic experimental multiple sclerosis.
other · Level V
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- Record sourced from PubMed, PMID 25906297.
- Also identified by DOI 10.1148/radiol.2015150059.
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Abstract
The report by Pulli et al ( 1 ) provides good preclinical evidence that MPO-Gd, a gadolinium-based magnetic resonance (MR) imaging probe for the enzyme myeloperoxidase (MPO), might be a more sensitive contrast agent for the detection of multiple sclerosis (MS) and may mark a pathologically specific proinflammatory component of the disease that might also provide the basis for novel therapies.
Medical subject headings
- Contrast Media
- Gadolinium DTPA
- Multiple Sclerosis
- Peroxidase