Gradients are shaping up.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25910201.
- Also identified by DOI 10.1016/j.cell.2015.04.009.
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Abstract
In animal embryos, morphogen gradients determine tissue patterning and morphogenesis. Shyer et al. provide evidence that, during vertebrate gut formation, tissue folding generates graded activity of signals required for subsequent steps of gut growth and differentiation, thereby revealing an intriguing link between tissue morphogenesis and morphogen gradient formation.
Medical subject headings
- Adult Stem Cells
- Intestine, Small
- Mechanotransduction, Cellular