Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25912610.
- Also identified by DOI 10.1039/c5lc00176e.
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Abstract
A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.
Medical subject headings
- Microfluidic Analytical Techniques
- Miniaturization
- Oligonucleotide Array Sequence Analysis
- Spectrometry, Fluorescence