High Molecular Weight Typing with MALDI-TOF MS - A Novel Method for Rapid Typing of Clostridium difficile.
Where this comes from
- Record sourced from PubMed, PMID 25923527.
- Also identified by DOI 10.1371/journal.pone.0122457 and PMC identifier 4414534.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Clostridium difficile strains were typed by a newly developed MALDI-TOF method, high molecular weight typing, and compared to PCR ribotyping. Among 500 isolates representing 59 PCR ribotypes a total of 35 high molecular weight types could be resolved. Although less discriminatory than PCR ribotyping, the method is extremely fast and simple, and supports for cost-effective screening of isolates during outbreak situations.
Medical subject headings
- Bacterial Typing Techniques
- Clostridioides difficile
- Clostridium Infections
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization