A general method for computing the Homfly polynomial of DNA double crossover 3-regular links.
basic_science · Level V
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- Record sourced from PubMed, PMID 25932998.
- Also identified by DOI 10.1371/journal.pone.0125184 and PMC identifier 4416910.
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Abstract
In the last 20 years or so, chemists and molecular biologists have synthesized some novel DNA polyhedra. Polyhedral links were introduced to model DNA polyhedra and study topological properties of DNA polyhedra. As a very powerful invariant of oriented links, the Homfly polynomial of some of such polyhedral links with small number of crossings has been obtained. However, it is a challenge to compute Homfly polynomials of polyhedral links with large number of crossings such as double crossover 3-regular links considered here. In this paper, a general method is given for computing the chain polynomial of the truncated cubic graph with two different labels from the chain polynomial of the original labeled cubic graph by substitutions. As a result, we can obtain the Homfly polynomial of the double crossover 3-regular link which has relatively large number of crossings.
Medical subject headings
- Computational Biology
- DNA
- Models, Molecular
- Nucleic Acid Conformation