An Adenine Code for DNA: A Second Life for N6-Methyladenine.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25936836.
- Also identified by DOI 10.1016/j.cell.2015.04.021.
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Abstract
DNA N6-methyladenine (6mA) protects against restriction enzymes in bacteria. However, isolated reports have suggested additional activities and its presence in other organisms, such as unicellular eukaryotes. New data now find that 6mA may have a gene regulatory function in green alga, worm, and fly, suggesting m6A as a potential "epigenetic" mark.
Medical subject headings
- Adenine
- DNA Methylation
- Epigenesis, Genetic