Immunology of protection from Ebola virus infection.

Krause, Philip R; Bryant, Paula R; Clark, Thomas; Dempsey, Walla; Henchal, Erik; Michael, Nelson L; Regules, Jason A; Gruber, Marion F · Sci Transl Med · 2015

review · Level V

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Abstract

A December 2014 meeting reviewed Ebola virus immunology relevant to vaccine development, including Ebola prevention, immunity, assay standardization, and regulatory considerations. Vaccinated humans appear to achieve immune responses comparable in magnitude with those associated with protection in nonhuman primates, suggesting that immunological data could be used to demonstrate vaccine efficacy.

Medical subject headings