A B cell-dependent mechanism restrains T cell transendothelial migration.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25951526.
- Also identified by DOI 10.1038/nm.3858 and PMC identifier 5980639.
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Abstract
A new study reveals that B cells restrict the transendothelial migration of T cells in physiological inflammation in response to adiponectin, but that this mechanism is compromised in autoimmunity and is hence a novel avenue for therapy development.
Medical subject headings
- Autoimmunity
- B-Lymphocytes
- Gene Expression Regulation
- Homeostasis
- Inflammation
- T-Lymphocytes