An Injectable, Self-Healing Hydrogel to Repair the Central Nervous System.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25953204.
- Also identified by DOI 10.1002/adma.201500762.
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Abstract
An injectable, self-healing hydrogel (≈1.5 kPa) is developed for healing nerve-system deficits. Neurosphere-like progenitors proliferate in the hydrogel and differentiate into neuron-like cells. In the zebrafish injury model, the central nervous system function is partially rescued by injection of the hydrogel and significantly rescued by injection of the neurosphere-laden hydrogel. The self-healing hydrogel may thus potentially repair the central nervous system.
Medical subject headings
- Biocompatible Materials
- Central Nervous System
- Hydrogel, Polyethylene Glycol Dimethacrylate
- Mechanical Phenomena