BFC: correcting Illumina sequencing errors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25953801.
- Also identified by DOI 10.1093/bioinformatics/btv290 and PMC identifier 4635656.
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Abstract
BFC is a free, fast and easy-to-use sequencing error corrector designed for Illumina short reads. It uses a non-greedy algorithm but still maintains a speed comparable to implementations based on greedy methods. In evaluations on real data, BFC appears to correct more errors with fewer overcorrections in comparison to existing tools. It particularly does well in suppressing systematic sequencing errors, which helps to improve the base accuracy of de novo assemblies. https://github.com/lh3/bfc hengli@broadinstitute.org Supplementary data are available at Bioinformatics online.
Medical subject headings
- Algorithms
- Computational Biology
- High-Throughput Nucleotide Sequencing
- Sequence Analysis, DNA