Mic10 Oligomerization Pinches off Mitochondrial Cristae.
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- Record sourced from PubMed, PMID 25955201.
- Also identified by DOI 10.1016/j.cmet.2015.04.020 and PMC identifier 4431669.
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Abstract
The mitochondrial contact site and cristae organizing system (MICOS) complex is essential for normal mitochondria biogenesis and morphology. In this issue, Bohnert et al. (2015) and Barbot et al. (2015) demonstrate that a MICOS core subunit, Mic10, is crucial for mitochondrial cristae formation by forming oligomers at the cristae junctions.
Medical subject headings
- Membrane Proteins
- Mitochondria
- Mitochondrial Membranes
- Mitochondrial Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins