Glycosaminoglycan and versican deposits in taxane-induced sclerosis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 25973640.
- Also identified by DOI 10.1111/bjd.13899.
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Abstract
Docetaxel and paclitaxel are widely used in the treatment of various malignant neoplasms. Taxane-induced sclerosis is dose-dependent and usually not generalized. Little information on the pathogenesis of scleroderma is currently available. Here, we report a case of generalized scleroderma and a case of early-stage oedematous sclerosis, both of which presented with intense versican deposits after administration of taxane for angiosarcoma.
Medical subject headings
- Glycosaminoglycans
- Scalp
- Scleroderma, Localized
- Taxoids
- Versicans