Bio-Enabled Gold Superstructures with Built-In and Accessible Electromagnetic Hotspots.

Tian, Limei; Fei, Max; Tadepalli, Sirimuvva; Morrissey, Jeremiah J; Kharasch, Evan D; Singamaneni, Srikanth · Adv Healthc Mater · 2015

basic_science · Level V

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Abstract

The bio-enabled synthesis of a novel class of surface enhanced Raman scattering probes is presented for functional imaging with built-in and accessible electromagnetic hotspots formed between densely packed satellites grown on a plasmonic core. The superstructures serve as nanoscale sensors to spatiotemporally map intravesicular pH changes along endocytic pathways inside live cells.

Medical subject headings