Obesity, Intrapancreatic Fatty Infiltration, and Pancreatic Cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25995340.
- Also identified by DOI 10.1158/1078-0432.CCR-15-0718.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Obesity and intrapancreatic fatty infiltration are associated with increased risk of pancreatic cancer and its precursor lesions. The interplay among obesity, inflammation, and oncogenic Kras signaling promotes pancreatic tumorigenesis. Targeting the interaction between obesity-associated inflammation and Kras signaling may provide new strategies for prevention and therapy of pancreatic cancer.
Medical subject headings
- Obesity
- Pancreas
- Pancreatic Neoplasms
- Precancerous Conditions