Fast size-determination of intact bacterial plasmids using nanofluidic channels.

Frykholm, K; Nyberg, L K; Lagerstedt, E; Noble, C; Fritzsche, J; Karami, N; Ambjörnsson, T; Sandegren, L et al. · Lab Chip · 2015

basic_science · Level V

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Abstract

We demonstrate how nanofluidic channels can be used as a tool to rapidly determine the number and sizes of plasmids in bacterial isolates. Each step can be automated at low cost, opening up opportunities for general use in microbiology labs.

Medical subject headings