Turning up the heat on membrane fluidity.

Fan, Weiwei; Evans, Ronald M · Cell · 2015

editorial · Level V

Where this comes from

Abstract

How do cells maintain the fluidity of cellular membrane in response to temperature fluctuation? In this issue of Cell, Ma et al. identify a regulatory circuit involving a heat-induced acyl-CoA dehydrogenase that controls the lipid saturation level and the fluidity of cellular membranes by transcriptionally regulating a lipid desaturase.

Medical subject headings