A CRISPR View of Cleavage.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26000476.
- Also identified by DOI 10.1016/j.cell.2015.05.003.
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Abstract
Seminal studies showed that CRISPR-Cas systems provide adaptive immunity in prokaryotes and promising gene-editing tools from bacteria to humans. Yet, reports diverged on whether some CRISPR systems naturally target DNA or RNA. Here, Samai and colleagues unify the studies, showing that a single type III CRISPR-Cas system cleaves both DNA and RNA targets, independently.
Medical subject headings
- CRISPR-Cas Systems
- Staphylococcus epidermidis