Serum level of vascular endothelial growth factor decreased in chronic ketamine abusers.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 26003336.
- Also identified by DOI 10.1016/j.drugalcdep.2015.04.022 and PMC identifier 4888963.
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Abstract
To evaluate the serum level of vascular endothelial growth factor (VEGF) in a group of chronic ketamine abusers in comparison to healthy controls. Eighty-one ketamine abusers who were hospitalized for the treatment of ketamine dependence and 39 healthy controls were recruited. Serum VEGF level was measured by enzyme linked immunosorbent assay (ELISA). Psychopathological symptoms were assessed using Positive and Negative Syndrome Scale (PANSS), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). Serum level of VEGF was significantly lower in chronic ketamine abusers compared to healthy controls (64.6±42.1 vs. 92.4±59.4pg/ml, F=7.243, p=0.008). Serum level of VEGF decreased in chronic ketamine abusers compared to healthy controls.
Medical subject headings
- Ketamine
- Substance-Related Disorders
- Vascular Endothelial Growth Factor A