GDF11 and the Mythical Fountain of Youth.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26003784.
- Also identified by DOI 10.1016/j.cmet.2015.05.009.
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Abstract
Identifying candidates that rejuvenate aged muscle stem cells is an important strategy toward developing therapies to treat age-related diseases. In this issue, Egerman et al. (2015) re-investigate the activity of GDF11 in myogenesis, recently suggested as an anti-aging agent, and instead find a potent inhibitory effect on skeletal muscle regeneration.
Medical subject headings
- Bone Morphogenetic Proteins
- Growth Differentiation Factors
- Muscle, Skeletal
- Regeneration