Ribavirin Reduces Absolute Lymphocyte Counts in Hepatitis C Virus-Infected Patients Treated With Interferon-Free, Direct-Acting Antiviral Regimens.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 26021996.
- Also identified by DOI 10.1093/cid/civ419.
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Abstract
In clinical trials of interferon-free, direct-acting antiviral treatment of chronic hepatitis C, subjects who received ribavirin had reduced lymphocyte levels (median decline of approximately 0.4-0.5 × 10(9) cells/L). A modest decline in CD4(+) T cells was observed in subjects with human immunodeficiency virus type 1 coinfection without documented opportunistic infections.
Medical subject headings
- Antiviral Agents
- Hepatitis C, Chronic
- Lymphopenia
- Ribavirin