Size doesn't matter; in the stroma, little things make all the difference.
Where this comes from
- Record sourced from PubMed, PMID 26024024.
- Also identified by DOI 10.1038/ki.2015.77.
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Abstract
In recent years there has been an increase in the number of studies into the role of stromal cells and microRNAs (miRNAs) in kidney development. Nakagawa et al. combine the two in a study of a stromal cell-specific knockout of Dicer1. The work identifies many important roles for miRNAs in these cells and kidney development in general, partially through their modification of the β-catenin signaling cascade.
Medical subject headings
- Cell Differentiation
- DEAD-box RNA Helicases
- Neovascularization, Physiologic
- Nephrons
- Ribonuclease III