DisVis: quantifying and visualizing accessible interaction space of distance-restrained biomolecular complexes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26026169.
- Also identified by DOI 10.1093/bioinformatics/btv333 and PMC identifier 4576694.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We present DisVis, a Python package and command line tool to calculate the reduced accessible interaction space of distance-restrained binary protein complexes, allowing for direct visualization and quantification of the information content of the distance restraints. The approach is general and can also be used as a knowledge-based distance energy term in FFT-based docking directly during the sampling stage. The source code with documentation is freely available from https://github.com/haddocking/disvis. a.m.j.j.bonvin@uu.nl Supplementary data are available at Bioinformatics online.
Medical subject headings
- Computer Graphics
- Data Interpretation, Statistical
- Proteasome Endopeptidase Complex
- RNA Polymerase II
- Software