The sum of all browning in FGF21 therapeutics.

Lee, Paul; Swarbrick, Michael M; Greenfield, Jerry R · Cell Metab · 2015

editorial · Level V

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Abstract

FGF21 mimetics are a promising therapeutic tool, believed to exert their anti-obesity effect partly through browning of white fat. Véniant et al. (2015) and Samms et al. (2015) present evidence arguing against fat browning as the primary mechanism causal to weight loss following FGF21-based treatment in mice.

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