FinisherSC: a repeat-aware tool for upgrading de novo assembly using long reads.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26040454.
- Also identified by DOI 10.1093/bioinformatics/btv280.
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Abstract
We introduce FinisherSC, a repeat-aware and scalable tool for upgrading de novo assembly using long reads. Experiments with real data suggest that FinisherSC can provide longer and higher quality contigs than existing tools while maintaining high concordance. The tool and data are available and will be maintained at http://kakitone.github.io/finishingTool/ : dntse@stanford.edu Supplementary data are available at Bioinformatics online.
Medical subject headings
- Algorithms
- Computational Biology
- Genomics
- High-Throughput Nucleotide Sequencing
- Repetitive Sequences, Nucleic Acid
- Sequence Analysis, DNA
- Software