Smart drug-loaded polymer gold nanoshells for systemic and localized therapy of human epithelial cancer.

Yang, Jaemoon; Lee, Jaewon; Kang, Jinyoung; Oh, Seung Jae; Ko, Hyun-Ju; Son, Joo-Hiuk; Lee, Kwangyeol; Suh, Jin-Suck et al. · Adv Mater · 2009

basic_science · Level V

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Abstract

Near-infrared-light-sensitive multifunctional smart drug-loaded polymer gold nanoshells are fabricated as advanced prototypes, composed of chemotherapeutic agents (therapeutic antibody and anticancer drug-loaded polymeric nanoparticles) for systemic chemotherapy of human epithelial cancer and a polymer-based gold nanoshell for localized photothermal treatment by NIR light.