It's a SMAD/SMAD World.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26046433.
- Also identified by DOI 10.1016/j.cell.2015.05.030.
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Abstract
DPC4/SMAD4 mutations are associated with aggressive pancreatic cancer. In this issue of Cell, Whittle et al. demonstrate that Runx3 expression combined with Dpc4/Smad4 status can predict the metastatic propensity of pancreatic tumors, providing valuable guidance for personalized therapy for patients with pancreatic cancer.
Medical subject headings
- Carcinoma, Pancreatic Ductal
- Core Binding Factor Alpha 3 Subunit
- Neoplasm Metastasis
- Pancreatic Neoplasms