Regulation of Muscle Satellite Cell Function in Tissue Homeostasis and Aging.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26046757.
- Also identified by DOI 10.1016/j.stem.2015.05.007 and PMC identifier 4492457.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Age-related muscle decline is associated with functional impairment of satellite cells (SCs). Conflicting data suggest dysregulation of cell-extrinsic or -intrinsic factors can independently contribute to such impairment. Here, we emphasize the importance of identifying nodes that integrate these factors into feed-forward circuits, which could provide targets for therapeutic intervention.
Medical subject headings
- Aging
- Homeostasis
- Satellite Cells, Skeletal Muscle