Spontaneous Regression of Pulmonary Lymphoepithelioma-Like Carcinoma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 26046875.
- Also identified by DOI 10.1016/j.athoracsur.2014.07.088.
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Abstract
The spontaneous regression of lung cancer is extremely rare. We encountered a case of a 70-year-old man with pulmonary lymphoepithelioma-like carcinoma that regressed without receiving anticancer therapy. The patient had depression during tumor regression, however, and was treated with a serotonin-selective reuptake inhibitor. On histologic examination, CD3(+), CD4(+), and CD8(+) lymphocytes were found to have infiltrated around the tumor. Thus, the serotonin-selective reuptake inhibitor may have activated these lymphocytes to cause spontaneous tumor regression.
Medical subject headings
- Adenocarcinoma, Papillary
- Lung Neoplasms
- Lymphocytes
- Neoplasm Regression, Spontaneous