Nonsteroidal anti-inflammatory drugs for treatment of acute gout.
Where this comes from
- Record sourced from PubMed, PMID 26057289.
- Also identified by DOI 10.1001/jama.2015.1881.
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Abstract
CLINICAL QUESTION: Are nonsteroidal anti-inflammatory drugs (NSAIDs) associated with better outcomes than cyclooxygenase inhibitors, glucocorticoids, IL-1 inhibitors or placebo in the treatment of acute gout? BOTTOM LINE: NSAIDs are not significantly associated with a difference in pain reduction compared with cyclooxygenase inhibitors and glucocorticoids for treating acute gout. However, NSAIDs are associated with higher rates of adverse events and higher rates of withdrawal due to adverse events compared with cyclooxygenase inhibitors.