Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26066510.
- Also identified by DOI 10.1371/journal.pone.0129695 and PMC identifier 4466802.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A guanine-rich DNA oligonucleotide complexed with hemin was used to catalyze controlled oxygen transfer reactions to different sulfides for sulfoxide preparation in the presence of H2O2. Comparable activities were obtained when using fully modified L-DNA. In addition, oligonucleotide immobilization led to an active catalyst which could be successfully recovered and reused without loss of activity.
Medical subject headings
- DNA
- Guanine
- Safrole