An acoustofluidic sputum liquefier.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26082346.
- Also identified by DOI 10.1039/c5lc00539f and PMC identifier 6518399.
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Abstract
We demonstrate the first microfluidic-based on-chip liquefaction device for human sputum samples. Our device is based on an acoustofluidic micromixer using oscillating sharp edges. This acoustofluidic sputum liquefier can effectively and uniformly liquefy sputum samples at a throughput of 30 μL min(-1). Cell viability and integrity are maintained during the sputum liquefaction process. Our acoustofluidic sputum liquefier can be conveniently integrated with other microfluidic units to enable automated on-chip sputum processing and analysis.
Medical subject headings
- Microfluidic Analytical Techniques
- Specimen Handling
- Sputum