Hepatitis B Virus Reactivation During Successful Treatment of Hepatitis C Virus With Sofosbuvir and Simeprevir.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 26082511.
- Also identified by DOI 10.1093/cid/civ474.
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Abstract
Treatment of hepatitis C virus with potent, interferon-free, direct-acting antiviral regimens with no activity against hepatitis B virus (HBV) may increase the risk for HBV reactivation in coinfected patients. We present 2 cases of HBV reactivation during treatment with an all-oral regimen of simeprevir and sofosbuvir and discuss strategies to prevent HBV flare.
Medical subject headings
- Antiviral Agents
- Coinfection
- Hepatitis B
- Hepatitis B virus
- Hepatitis C, Chronic
- Simeprevir
- Sofosbuvir