Boronate-Phenolic Network Capsules with Dual Response to Acidic pH and cis-Diols.

Guo, Junling; Sun, Huanli; Alt, Karen; Tardy, Blaise L; Richardson, Joseph J; Suma, Tomoya; Ejima, Hirotaka; Cui, Jiwei et al. · Adv Healthc Mater · 2015

basic_science · Level V

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Abstract

Dual-responsive boronate-phenolic network (BPN) capsules are fabricated by the complexation of phenylborate and phenolic materials. The BPN capsules are stable in the presence of competing carbohydrates, but dissociate at acidic pH or in the presence of competing cis-diols at physiological pH. This engineered capsule system provides a platform for a wide range of biological and biomedical applications.

Medical subject headings